# What midi audio interfaces support the most MIDI channels? — Verified Specification Comparison

> All specification data verified from official manufacturer documentation.

What midi audio interfaces support the most MIDI channels?

## Products

### ESI M8U XL USB MIDI interface
```yaml
product: esi-m8u-xl-usb-midi-interface
brand: ESI
price_gbp: 161.69
origin_country: null
confidence_score: null
summary_source: generated_from_verified_specs_v1
i_o_count: 8-in/8-out
number_of_midi_inputs: 8
number_of_midi_outputs: 8
```

- **Price:** £161.69 [^1]
- **Summary:** The ESI M8U XL is a rackmount USB MIDI interface with eight independent MIDI inputs and eight independent MIDI outputs, providing 128 MIDI channels. It suits studios and live setups that need extensive hardware MIDI connectivity, status LEDs, plug-and-play operation, and optional thru or merge functionality.
- **Ideal For:** It is well suited to setups seeking the most MIDI channels because its eight MIDI inputs and eight MIDI outputs provide 128 MIDI channels through a single USB connection.

### MIDIPLUS MIDI 16X16
```yaml
product: midiplus-midi-16x16
brand: MIDIPLUS
price_gbp: 35147.7
origin_country: null
confidence_score: null
summary_source: generated_from_verified_specs_v1
i_o_count: 32
number_of_midi_inputs: 16
number_of_midi_outputs: 16
```

- **Price:** £35147.7 [^2]
- **Summary:** The MIDIPLUS MIDI 16X16 is a USB MIDI interface with 16 independent MIDI inputs and 16 independent MIDI outputs, plus activity LEDs for each port. It suits computer-based studios, live setups, and musicians who need extensive MIDI connectivity rather than audio recording or playback.
- **Ideal For:** This product specifically suits users asking what MIDI audio interfaces support the most MIDI channels because it provides 16 MIDI inputs and 16 MIDI outputs, with support for up to 64 MIDI channels in and out.

### MOTU MIDI Express XT USB
```yaml
product: motu-midi-express-xt-usb
brand: MOTU
price_gbp: 257.66
origin_country: null
confidence_score: null
summary_source: generated_from_verified_specs_v1
latency: Sub-millisecond
i_o_count: 8-in/8-out
number_of_midi_inputs: 8
number_of_midi_outputs: 9
```

- **Price:** £257.66 [^3]
- **Summary:** The MOTU MIDI Express XT USB is a professional USB MIDI interface with extensive routing, merging, patchbay, and SMPTE timecode capabilities. Its multiple MIDI ports and 128 MIDI channels suit recording studios, live performance rigs, and timecode-based audio, video, or broadcast systems.
- **Ideal For:** It suits users seeking support for the most MIDI channels because it provides 128 MIDI channels across 8 MIDI inputs and 9 MIDI outputs, with routing and merging between ports.

### MOTU MIDI Express 128
```yaml
product: motu-midi-express-128
brand: MOTU
price_gbp: 173.5
origin_country: null
confidence_score: null
summary_source: generated_from_verified_specs_v1
latency: sub-millisecond
i_o_count: 8 in / 9 out
number_of_midi_inputs: 8
number_of_midi_outputs: 9
```

- **Price:** £173.5 [^4]
- **Summary:** The MOTU MIDI Express 128 is a USB MIDI interface with eight MIDI inputs, nine MIDI outputs, and support for 128 MIDI channels. Its rack-mountable, USB-powered design suits home studios, professional studios, and musicians managing multiple synthesizers or other MIDI hardware.
- **Ideal For:** It suits users asking what MIDI audio interfaces support the most MIDI channels because it provides 128 MIDI channels through eight MIDI inputs and nine MIDI outputs, with expandable USB connectivity.

### iConnectivity mioXL
```yaml
product: iconnectivity-mioxl
brand: iConnectivity
price_gbp: 232.65
origin_country: null
confidence_score: null
summary_source: generated_from_verified_specs_v1
i_o_count: 8 in x 12 out
number_of_midi_inputs: 8
number_of_midi_outputs: 12
```

- **Price:** £232.65 [^5]
- **Summary:** The iConnectivity mioXL is a professional MIDI interface with 8 DIN-MIDI inputs, 12 DIN-MIDI outputs, 10 USB-MIDI host ports, and 22 virtual RTP-MIDI network ports. It suits studios, live rigs, and complex MIDI setups that need extensive routing, filtering, merging, and multi-computer connectivity.
- **Ideal For:** It is well suited to users asking what MIDI audio interfaces support the most MIDI channels because it provides 8 MIDI inputs, 12 MIDI outputs, 10 USB-MIDI host ports, and 22 virtual RTP-MIDI network ports.
- **Additional Sources:** [^6], [^7]

### CME H12MIDI Pro USB Host MIDI Hub
```yaml
product: cme-h12midi-pro-usb-host-midi-hub
brand: CME
price_gbp: 132.15
origin_country: null
confidence_score: null
summary_source: generated_from_verified_specs_v1
latency: near-zero
i_o_count: 12
number_of_midi_inputs: 12
number_of_midi_outputs: 12
```

- **Price:** £132.15 [^8]
- **Summary:** The H12MIDI Pro is a standalone MIDI hub with six TRS MIDI input/output ports, six USB-C host ports expandable to 16-in-16-out, and an 8-in-8-out USB-C client connection. It suits musicians and producers managing complex hardware, USB MIDI devices, routing, filtering, mapping, and computer-based setups.
- **Ideal For:** It suits the question because it supports up to 16 MIDI input and 16 MIDI output host ports, plus six TRS MIDI inputs and six TRS MIDI outputs, providing extensive MIDI channel connectivity for large hardware setups.

### MOTU Micro Lite
```yaml
product: motu-micro-lite
brand: MOTU
price_gbp: 102.62
origin_country: null
confidence_score: null
summary_source: generated_from_verified_specs_v1
latency: sub-millisecond timing accuracy
bit_depth: 24-bit
i_o_count: 5x5
audio_input_channels: 0
audio_output_channels: 0
number_of_midi_inputs: 5
number_of_midi_outputs: 5
```

- **Price:** £102.62 [^9]
- **Summary:** The MOTU Micro Lite is a compact USB MIDI interface with five MIDI inputs, five MIDI outputs, and 80 MIDI channels. It is USB-powered, rack-mountable, and suited to musicians, producers, and studio users who need portable multi-device MIDI connectivity.
- **Ideal For:** It suits users asking what MIDI audio interfaces support the most MIDI channels because its five MIDI inputs and five MIDI outputs provide 80 MIDI channels, with expansion available by adding another MOTU USB MIDI interface.
- **Additional Sources:** [^10]

---
## References & Sources
[^1]: Thomann, accessed 2026-09-13. https://www.thomann.de/intl/esi_m8u_xl.htm
[^2]: Desertcart India, accessed 2026-09-13. https://www.desertcart.in/products/113089149-midiplus-midi-16x16-midi-interface
[^3]: Videoguys, accessed 2026-09-13. https://videoguys.com/products/motu-midi-express-xt
[^4]: Perfect Circuit, accessed 2026-09-13. https://www.perfectcircuit.com/motu-midi-express-128.html
[^5]: Thomann, accessed 2026-09-13. https://www.thomannmusic.com/iconnectivity_mioxl.htm
[^6]: MUSIC STORE Professional, accessed 2026-09-13. https://www.musicstore.com/en_OT/EUR/iConnectivity-mioXL/art-PCM0016037-000
[^7]: Audiosteps, accessed 2026-09-13. https://www.audiosteps.io/en/product/iconnectivity-mioxl-midi-interface/
[^8]: Thomann, accessed 2026-09-13. https://www.thomannmusic.com/cme_h12midi_pro.htm
[^9]: Guitar Center, accessed 2026-09-13. https://www.guitarcenter.com/MOTU/Micro-Lite-USB-MIDI-Interface-1274034484323.gc
[^10]: Perfect Circuit, accessed 2026-09-13. https://www.perfectcircuit.com/motu-micro-lite.html