Product Price Active Ingredient Dosage Frequency Duration (months) Waterproof Suitable for Puppies Potential Side Effects Application Method
NexGard NexGard afoxolaner Chewables for Dogs
US
£67.45 Afoxolaner 11.3 mg, 28.3 mg, 68 mg, or 136 mg per chew Once monthly 30 days Oral soft chew, with or without food

NexGard is a beef-flavored oral chew containing afoxolaner that kills fleas and controls several tick species for 30 days. It is suitable for dogs and puppies from 8 weeks of age weighing at least 4 lbs and is given once monthly.

★ Ideal for

NexGard suits shoppers seeking reliable flea and tick prevention because its afoxolaner chew is FDA-approved, works for 30 days, kills fleas before they lay eggs, and is suitable for puppies from 8 weeks of age.

Frontline Frontline Plus fipronil and S-methoprene Flea and Tick Topical for Dogs
US
£19.66 Fipronil 9.8% and S-methoprene 8.8% Once monthly 30 days Apply the full applicator contents to the skin between the shoulder blades

Frontline Plus is a monthly topical treatment containing fipronil and S-methoprene to control fleas and ticks, including flea eggs and larvae. It is waterproof after drying and is suitable for dogs and puppies at least 8 weeks old and weighing at least 5 lbs.

★ Ideal for

This product suits owners seeking reliable dog flea and tick prevention because it combines two active ingredients, provides 30 days of protection, is waterproof, and targets multiple flea life stages.

K9 Advantix K9 Advantix II permethrin and imidacloprid Topical for Dogs
US
£46.13 Imidacloprid 8.80%, permethrin 44.00%, pyriproxyfen 0.44% Every 30 days 30 days Apply the entire tube to 2 to 3 spots on the skin along the back from the shoulders to the base of the tail

K9 Advantix II is a monthly topical treatment that kills and repels fleas, ticks, mosquitoes, biting flies, and lice through contact. It is waterproof after 24 hours and is suitable for dogs and puppies at least 7 weeks old that meet the applicable weight requirement.

★ Ideal for

K9 Advantix II suits owners seeking reliable dog flea and tick prevention because its imidacloprid, permethrin, and pyriproxyfen formula provides monthly protection, repels ticks before attachment, and remains waterproof after 24 hours.